Paul Ellis, Ph.D.

Expertise

Paul Ellis

Nuclear Magnetic Resonance Spectroscopy

Phenomenological Theory—static and dynamic lineshape analysis and the extraction of NMR parameters from these lineshapes
Molecular Theory of Magnetic Resonance Parameters—chemical shifts, quadrupole coupling constants, indirect nuclear spin couplings
Multinuclear Magnetic Resonance Methods
Application of DNP Methods to Surfaces

Structural Biology

Structure/Function Relationships in DNA Repair and Bioremediation Proteins
Structure/Function Relationships in Metallobiochemistry
Application of Ultra High Field Magnetic Resonance Methods to Problems in Structural Biology

Heterogeneous Catalysis

Structure and Dynamics of Small Molecules Adsorbed to Oxide Surfaces and Metals on Oxide Supports
Elucidation of the Role of Promoters in Catalysis
Exploration of Catalytic Dechlorination Reactions

Education

Ph.D., Chemistry, University of California at Davis, 1970
B.S., Physical Chemistry, University of California at Davis, 1966

Honors and Awards

Fellow of American Association for the Advancement of Science, 2003.
Member of the Committee on Opportunities in High Magnetic Field Science, under the auspices of the Board on Physics and Astronomy for the National Academies of Science, 2003-2005 .
Member of the Natural Sciences and Engineering Research Council (NSERC) of Canada’s Major Facilities Access Committee (GSC 99), 2004-2007.
Member of the Executive Committee for the Council of Fellows at Pacific Northwest National Laboratory, 2006-2009.
Member of the Committee on Opportunities in High Magnetic Field Science, under the auspices of the Board on Physics and Astronomy for the National Academies of Science, 2003-2005
Fellow of American Association for the Advancement of Science, 2003
Member Editorial Board of the Journal of Magnetic Resonance, 2002
National Institutes of Health Reviewers Reserve, 1995-1999
Pacific Northwest National Laboratory Fellow, 1999
Member BBCA Study Section: National Institutes of Health General Medical Sciences, 1991-1995
World Bank Visiting Scholar in China, 1991
Corecipient of the South Carolina Governor’s Award for Excellence in Science, 1990
Editorial Advisory Board for "Concepts in Magnetic Resonance," 1989-1995
Advisory Committee for the Biological Facilities Centers Program, NSF, 1987-1989
Chairman, Gordon Conference on Magnetic Resonance in Biology and Medicine, 1986
South Carolina Chemist of the Year, awarded by the SC section of the ACS, 1985
Editorial Advisory Board for “Magnetic Resonance in Chemistry”, 1984-1996
Chairman Elect, Gordon Conference on Magnetic Resonance in Biology and Medicine, 1984
Director Regional Instrumentation Facility in NMR Spectroscopy Sponsored by the National Science Foundation, 1978-1988
Chairman, Experimental NMR Conference, 1977
A.P. Sloan Foundation Fellow, 1977-1979
Russell Award for Science and Engineering, 1976

Professional Society

International Society of Magnetic Resonance

Selected Publications

Lipton AS, RW Heck, M Valiev, and PD Ellis. 2008. "A QM/MM Approach to Interpreting ⁶⁷Zn Solid-State NMR Data in Zinc Proteins," J. Am. Chem. Soc., 130, 6224 – 6230.

Lipton AS, MM Morlok, G Parkin, and PD Ellis. 2008. "⁶⁷Zn Solid State NMR Spectroscopy of {[Tp^tert-Bu,Me]Zn(OH₂)}[HOB(C₆F₅))₃]. The Importance of the Anion, [HOB(C₆F₅))₃]^-," Inorg. Chem., 47(12), 5148 – 5189.

Lipton AS, RW Heck, S Primak, DR McNeill, DM Wilson III, and PD Ellis. 2008. "Characterization of the Mg²⁺ Binding to the DNA Repair Proteins Apurinic/Apyrimidic Endonuclease 1 (APE1) via Solid-State ²⁵Mg NMR Spectroscopy," J. Am. Chem. Soc., 130, 9332 – 9341.

Lipton AS, RW Heck, M Hernick, CA Fierke, and PD Ellis. 2008. "Residue Ionization in LpxC Directly Observed by ⁶⁷Zn NMR Spectroscopy," J. Am. Chem. Soc., 130(38), 12671 – 12679.

Lipton AS, and PD Ellis. 2007. "Modeling the Metal Center of Cys₄ Zinc Proteins," J. Am. Chem., Soc., 129(29), 9192 – 9200.

Contact Information

Paul.Ellis@pnl.gov