Paul Ellis, Ph.D.
Expertise
Paul Ellis
Nuclear Magnetic Resonance Spectroscopy
- Phenomenological Theory--static and dynamic lineshape analysis and the extraction of NMR parameters from these lineshapes
- Molecular Theory of Magnetic Resonance Parameters--chemical shifts, quadrupole coupling constants, indirect nuclear spin couplings
- Multinuclear Magnetic Resonance Methods
- Application of DNP Methods to Surfaces
Structural Biology
- Structure/Function Relationships in DNA Repair and Bioremediation Proteins
- Structure/Function Relationships in Metallobiochemistry
- Application of Ultra High Field Magnetic Resonance Methods to Problems in Structural Biology
Heterogeneous Catalysis
- Structure and Dynamics of Small Molecules Adsorbed to Oxide Surfaces and Metals on Oxide Supports
- Elucidation of the Role of Promoters in Catalysis
- Exploration of Catalytic Dechlorination Reactions
Education
- Ph.D., Chemistry, University of California at Davis, 1970
- B.S., Physical Chemistry, University of California at Davis, 1966
Honors and Awards
- Fellow of American Association for the Advancement of Science, 2003.
- Member of the Committee on Opportunities in High Magnetic Field Science, under the auspices of the Board on Physics and Astronomy for the National Academies of Science, 2003 – 2005 .
- Member of the Natural Sciences and Engineering Research Council (NSERC) of Canada’s Major Facilities Access Committee (GSC 99), 2004 – 2007.
- Member of the Executive Committee for the Council of Fellows at Pacific Northwest National Laboratory, 2006 – 2009.
- Member of the Committee on Opportunities in High Magnetic Field Science, under the auspices of the Board on Physics and Astronomy for the National Academies of Science, 2003-2005
- Fellow of American Association for the Advancement of Science, 2003-
- Member Editorial Board of the Journal of Magnetic Resonance, 2002-
- National Institutes of Health Reviewers Reserve, 1995-1999
- Pacific Northwest National Laboratory Fellow, 1999
- Member BBCA Study Section: National Institutes of Health General Medical Sciences, 1991-1995
- World Bank Visiting Scholar in China, 1991
- Corecipient of the South Carolina Governor’s Award for Excellence in Science, 1990
- Editorial Advisory Board for "Concepts in Magnetic Resonance," 1989-1995
- Advisory Committee for the Biological Facilities Centers Program, NSF, 1987-1989
- Chairman, Gordon Conference on Magnetic Resonance in Biology and Medicine, 1986
- South Carolina Chemist of the Year, awarded by the SC section of the ACS, 1985
- Editorial Advisory Board for “Magnetic Resonance in Chemistry”, 1984-1996
- Chairman Elect, Gordon Conference on Magnetic Resonance in Biology and Medicine, 1984
- Director Regional Instrumentation Facility in NMR Spectroscopy Sponsored by the National Science Foundation, 1978-1988
- Chairman, Experimental NMR Conference, 1977
- A.P. Sloan Foundation Fellow, 1977-1979
- Russell Award for Science and Engineering, 1976
Professional Society
- International Society of Magnetic Resonance
Selected Publications
P. D. Ellis and A. S. Lipton; "Low Temperature Solid-State NMR Spectroscopy. A Strategy for the Direct Observation of Quadrupolar Nuclides of Biological Interest," Chapter 1 in Vol. 60 of Annual Reports in NMR Spectroscopy, Ed by G. A. Webb, pages 1-38, 2007.
A. S. Lipton and P. D. Ellis, "Modeling the Metal Center of Cys4 Zinc Proteins," J. Am. Chem., Soc., 129(29), 9192 – 9200 (2007).
A. S. Lipton, R. W. Heck, M. Valiev, and P. D. Ellis, "A QM/MM Approach to Interpreting 67Zn Solid-State NMR Data in Zinc Proteins," J. Am. Chem. Soc., 130, 6224 – 6230 (2008).
H. Cho, W. J. Shaw, V. Parvanov, G. K. Schenter, A. Karkamkar, N. J. Hess, C. Mundy, S. Kathmann, J. Sears, A. S. Lipton, P. D. Ellis, and S. T. Autrey, J. Phys. Chem., 112, 4277 – 4283 (2008).
A. S. Lipton, R. W. Heck, M. Valiev, and P. D. Ellis, "A QM/MM Approach to Interpreting 67Zn Solid-State NMR Data in Zinc Proteins," J. Am. Chem. Soc., 130, 6224 – 6230 (2008).
A. S. Lipton, M. M. Morlok, G. Parkin, and P. D. Ellis, "67Zn Solid State NMR Spectroscopy of {[Tptert-Bu,Me]Zn(OH2)}[HOB(C6F5))3]. The Importance of the Anion, [HOB(C6F5))3]-," Inorg. Chem., 47(12), 5148 – 5189 (2008).
A. S. Lipton, R. W. Heck, S. Primak, D, R. McNeill, D. M. Wilson III, and P. D. Ellis, "Characterization of the Mg2+ Binding to the DNA Repair Proteins Apurinic/Apyrimidic Endonuclease 1 (APE1) via Solid-State 25Mg NMR Spectroscopy," J. Am. Chem. Soc., 130, 9332 – 9341 (2008).
Andrew S. Lipton, Robert W. Heck, Marcy Hernick, Carol A. Fierke, and Paul D. Ellis "Residue Ionization in LpxC Directly Observed by 67Zn NMR Spectroscopy," J. Am. Chem. Soc., 130(38), 12671 – 12679 (2008).
A. S. Lipton, T. Polenova, and P. D. Ellis, "Quadrupolar Metal Nuclieds in Bioinorganic Chemistry: Solid-State NMR Studies," Encyclopedia of NMR Spectroscopy, in press.
A. S. Lipton, R. W. Heck, J. A. Sears, S. X. Ni, J. V. Hanna, R. G. Bryant, and P. D. Ellis, "The Low Temperature 43Ca NMR Spectroscopy of Ca2+ Binding Protein Calbindin D9k, submitted to J. Am. Chem. Soc.
A. S. Lipton, R. W. Heck, W. A. deJong, A. R. Gao, X. Wu, A Roehrich, G. Harbison, and P.D Ellis, "Low Temperature 65Cu NMR Spectroscopy of the Cu1+ site in Azurin," submitted to J. Am. Chem. Soc.