Applying Proteomics Capabilities to Research
Scientists at PNNL apply our existing capabilities to research funded by both private Laboratory Research and Development and public sources (e.g., U.S. Department of Energy and National Institutes of Health). New capabilities are created through Laboratory Research and Development.
Proteomic Projects
Projects supported by Laboratory Research and Development
- Mechanisms of Regulated Ligand Shedding
- High-Throughput Isolation of Organelles
- Proteomics of Membrane Proteins: Relating Calcium Signaling and Oxidative Stress
- Functional Genomic Analysis of the Regulation of Bone Cells by a Bioactive Lipid
- Fast, Two-Dimensional Gas-Phase Separations for Ultrahigh-Throughput Global Analyses
- Quantitative Characterization of Post-Translational Protein Modifications Using Mass Spectrometry
- Affinity Reagents Based on Novel Molecular Scaffolds
- Array Technologies for Quantification of Proteins
- Proteome and Bioenergetic Analysis of Growth States in a Syntrophic Co-Culture
Projects supported by U.S. Department of Energy Office of Science Genomics:GTL
Projects supported by U.S. Department of Energy Low Dose Radiation Research Program
- Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation
- Molecular Mechanisms Underlying Cellular Adaptive Response to Low Dose Radiation
Projects supported by U.S. Department of Energy Office of Science Environmental Remediation Sciences Program
Projects Supported by the National Institutes of Health
- Proteomics National Center for Research Resource
- Proteomic Identification of NAF Biomarkers
- High-Throughput Evaluation of Breast Cancer Markers
- Proteomics and Metabolomics Studies of Type 1 Diabetes
- Advanced Proteomics and Metabolomics: Type 2 Diabetes and Pre-Diabetes
- Identifying Targets for Therapeutic Interventions of Salmonella Bacteria and Orthopox Viruses Using Proteomic Technology
- High-Throughput Proteomics for Trauma Research with the Inflammation and the Host Response to Injury Consortium
- Transcriptome and Proteome Mapping of the Mouse Brain
- Development of Antibody Microarrays for the National Cancer Institute Early Detection Research Network
- Center for Functional Genomics and HCV-Associated Liver Disease
- Center for Genomic Experimentation and Computation
- High Dynamic Range Quantitative Proteomic Profiling of Plasma Samples from Pre-diagnostic Colon Cancer Patients and Controls