Seminars and Workshops
Systems Genomics 2008
May 2-3, 2008
Heidelberg, Germany
Bioinformatics of Genome Regulation and Structure
June 22-29
Novosibirsk, Russian Federation
Recently Held Seminars and Workshops
Joint Receptor Tyrosine Kinase (RTK) Consortium & British Society for Proteome Research/European Bioinformatics Institute Workshop
July 23-24, 2007
Cambridge, UK
4th Joint BSPR/EBI Proteomics meeting: Integrative Proteomics: Maximising the Value of Proteomics
July 25-27, 2007
Cambridge, UK

Mudita Singhal demonstrating the Bioinformatics Resource Manager Software.
American Society for Cell Biology Meeting
December 9-13, 2006
San Diego, CA, USA
PNNL participated in the 2006 American Society for Cell Biology Meeting December 9-13, 2006 at the San Diego Convention Center, San Diego, CA. We had a booth in the meeting exhibit hall, "Systems Biology at the Cellular Level," where Mudita Singhal demonstrated PNNL’s Bioinformatics Resource Manager software.
Other activities:
- Steve Wiley presented a talk December 10 at a minisymposium on Computational Applications in Cell Biology entitled "Analysis and Modeling of the Rapid ERK Oscillations That Occur in Response to EGF Receptor Activation."
- Katrina Waters and Steve held a Special Interest Subgroup meeting December 9 entitled “Managing the Data Explosion in Systems Biology.”
- Steve Wiley held a tutorial December 11 entitled “Multiparametric Live-Cell Imaging for Systems Biology.”
MGED 9 - The Meeting of the Microarray Gene Expression Data Society
September 7 - 10, 2006
Seattle, WA, USA
PNNL scientists presented posters showcasing their bioinformatics research at this year's meeting. Ron Taylor and Banu Gopalan presented their work on "Software Environment for Biological Network Inference (SEBINI)".
AAAS Annual Meeting
February 16-20, 2006
St. Louis, MO
PNNL scientist S.K. Sundaram organized the symposium on "Toxicology of Nanoparticles" as part of the AAAS 2006 Nanotechnology Seminar. PNNL participants in this particular symposium included:
- Rick Corley, Virtual Respiratory Tract Model
- Tom Weber, Real-time Monitoring of PM-Lung Cell Interactions I: Biology and Spectroscopy
- S.K. Sundaram, Real-time Monitoring of PM-Lung Cell Interactions II: Functionalization and Cell Adhesion
The American Society for Cell Biology (ASCB)
December 10-14, 2005
San Francisco, CA
This is the fourth year the PNNL has exhibited at the international meeting, and this year's theme was “Systems Science at the Molecular Level.” In addition to poster and oral presentations by PNNL scientists, PNNL also held a tutorial entitled "Apples and Oranges: Integrating Disparate Data Sets to Understand Complex Cellular Function" (PDF, 2.4M).
Receptor Tyrosine Kinase Consortium Workshop followed the International Conference on Systems Biology (ICSB) Sunday, October 23, 9:00 to 13:15 in Boston, Massachusetts, USA
Location: The Rotunda Room, Harvard Medical Conference Center
The aim of the workshop was to inform the systems biology community of the RTK Consortium's goals and to elicit the community's input to develop an effective agenda for implementing these goals. The meeting included oral and poster presentations by current Consortium members and other interested investigators, followed by an extended discussion.
Big Biofilm Bash
University of Southern California School of Dentistry
October 24-28, 2005
Los Angeles, CA
Invited speaker PNNL scientist Paul Majors presented on, "NMR microscopy for the in situ examination of bacterial physiology."
Third Annual Protein Biomarkers 2005September 26-28, 2005
Philadelphia, PA
PNNL scientist, Richard Zangar presented, "Biomarker Discovery and Validation Using Accurate Mass and Time Tag (AMT) Proteomics and ELISA Microarrays." Discovery of new cancer biomarkers is problematic due to the limited sensitivity and throughput of proteomic methods combined with the heterogeneity of the human population. To overcome these challenges, we are evaluating nipple aspirate fluid (NAF), a concentrated source of breast proteins, using a very sensitive proteomics method called the accurate mass and time tag (AMT) approach. Biomarker candidates identified in the proteomic studies will be validated in plasma and NAF using an ELISA microarray system that can simultaneously analyze up to 50 candidate biomarkers. This system can process sufficient numbers (i.e., thousands) of plasma samples to evaluate the effects of potentially confounding factors such as age, race, weight, etc. on the clinical utility of a biomarker or profile of biomarkers.
The 2005 Northwest Symposium for Systems Biology: Toward a Predictive Science
June 20 and 21 2005
EMSL Auditorium, PNNL campus
Richland, WA
This year's symposium focused on the process of driving systems biology toward the ability to predict complex biological systemic behaviors via three engaging sessions: Generating the Data Needed for Prediction; Generating Models that Predict; and Applications: Brave New world. Special keynote presentation was given by Dr. David Galas , V.P., Chief Scientific Officer for Biological and Life Sciences Battelle Memorial Institute.
The American Society for Microbiology
105th General Meeting in the Georgia World Congress Center
June 5-9, 2005
Atlanta, GA
The scientific program featured nearly 300 individual colloquia, symposia, roundtable discussions, award lectures, and poster sessions. The 27 division chairs and the General Meeting Program Committee have devoted their energies to creating a well-rounded program. PNNL was well represented as attendees and presenters. James Fredrickson chaired a session entitled, “Dealing with Hypothetical Proteins; Integrative Microbiology Perspectives. Margie Romine gave a talk at this session with a focus on hypothetical'sin Shewanella oneidensis. Jeff Mclean presented a poster entitled, “Estimating Biofilm Properties Using an Acoustic Microscope.”
Institute
for Systems Biology
4th Annual International Symposium
April 24-25, 2005
Seattle, WA
PNNL co-hosted this year's Institute for Systems Biology (ISB) symposium which addressed the computational challenges that researchers face in systems biology. Speakers represented research areas such as Computational Genomics and Bioengineering. The keynote address was given by Nathan Myhvold, founder of Intellectual Ventures, LLC. The symposium theme was guided by the philosophy that technology can revolutionize biological discovery and participants explored the computational challenges and their role in the exploration of new frontiers in biology and medicine in the 21st Century.
AAAS
Annual Meeting
The Nexus: Where Science Meets Society
February 17-21, 2005
Washington D.C.
In conjunction with the annual AAAS meeting on February 19, 2005, the Biomolecular Systems Initiative organized an all day seminar or “Inundated with Data – the -Omics Revolution”. The seminar was chaired by Karin Rodland, and invited speakers from BSI included Steve Wiley and George Michaels. The seminar was co-organized by Valda Vinson, Associate Editor of Science magazine.
The focus of the day-long seminar was high-throughput biology and it’s potential to change the way we do research. High throughput biology is the newest technical revolution in the life sciences, with as much potential to change research as the recombinant biology revolution of the 70s and 80s. The trend is to capture data – lots and lots of data – about lots and lots of biological endpoints. The -OMICS explosion simply reflects all the different molecules that can now be measured accurately and rapidly: genes, mRNA, proteins, metabolites, sugars, lipids, and more. But what do you do with all these data once you have them? There are technical issues: how to determine the quality of the data, how to store and transmit the data, how to integrate the data types? But even more important are the practical issues – what new insights do these large data sets provide? Will we ever be able to know completely the workings of a single cell, let alone predict the response to insult, or to therapy? These are the goals of systems biology, and high throughput biology provides the tools needed to attain those goals. The seminar had over 100 attendees at all three sessions and a lively question and answer period, particularly regarding the need for open access to data and common data standards.
Tutorials
Noontime Seminar Series: Computational
Biology & Bioinformatics (Spring 2004)
hosted by PNNL and Washington State University Tri-Cities
