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Katrina M. Waters, Ph.D.

Katrina M. Waters
Katrina M. Waters

Expertise

Dr. Waters’ research interests are focused around the analysis and biological interpretation of gene expression profiling data as it relates to mechanistic questions or applied research, such as biomarker discovery. In addition, she has several years experience developing and carrying out molecular and biochemical assays in the laboratory to test hypotheses resulting from microarray experiments. Her previous work at Merck Research Labs was in the area of investigative toxicology, supporting the safety assessment of drug development candidates and biomarker discovery efforts.

Education

Honors and Awards

Selected Publications

Rickard DJ, Waters KM, Ruesink TJ, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Riggs BL, Spelsberg TC. 2002. "Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts." J Bone Miner Res. 17(4):580-92.

Waters KM, S Safe, and KW Gaido. 2001. "Differential gene expression in response to methoxychlor and estradiol through ERα, ERβ and AR in reprod uctive tissues of female mice." Toxicological Sciences 63, 47-56.

Waters KM, DJ Rickard, BL Riggs, S Khosla, JA Katzenellenbogen, BJ Katzenellenbogen, JT Moore, and TC Spelsberg. 2001. "Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform." Journal of Cellular Biochemistry 83, 448-462.

Hefferan TE, GG Reinholz, KM Waters, M Subramaniam, and TC Spelsberg. 2000. "TGF-β inducible early gene (TIEG) overexpression mimics TGF-β action in human osteoblast cells." Journal of Biological Chemistry 275, 20255-20259.

Robinson JA, KM Waters, RT Turner, and TC Spelsberg. 2000. "Direct action of naturally occurring estrogen metabolites on human osteoblastic cells." Journal of Bone and Mineral Research 15, 499-506.

Contact Information

katrina.waters@pnl.gov