Ronald C. Taylor, Ph.D.
Expertise
Ronald C. Taylor
Reconstruction of biological networks, development of algorithms for inference of regulatory networks focused on information-theoretic and graphical model (Bayesian network) approaches, programmatic integration of network inference algorithms, high throughput analysis of gene expression and protein abundance data, automated reasoning and machine learning techniques as applied to analysis of metabolic and signaling pathways and genomic data, biological database design, biological data transfer standards, development of computational biology tools.
Education
- Ph.D., Bioinformatics, George Mason University, 2003
- M.S., Biology, Case Western Reserve University, 1991
- M.S., Computer Science, Case Western Reserve University, 1985
- B.S., Physics, Case Western Reserve University, 1979
Professional Affiliations
- Secretary 2000-2006, Treasurer 2006-present, Microarray and Gene Expression Data (MGED) Society
- Founder and chair, National Institutes of Health inter-institute Java Interest Group, 1997-2000
- Member, International Society for Computational Biology, 1997-present
Honors and Awards
- Outstanding Mentor Award, US Department of Energy, Office of Science, 2006
- Navachat Tongvichat Bioinformatics Memorial Scholarship, George Mason University, 2001
- NIH Employee Sustained Superior Performance Award, 1999
- NIH Employee Sustained Superior Performance Award, 1998
- NIH DCRT divisional web site award, 1996
- Honors commendation, HHS Project Officer Course, 1994
- NIH Employee Sustained Superior Performance Award, 1993
- NIH Employee Sustained Superior Performance Award, 1992
- Argonne National Laboratory (Department of Energy) Graduate Assistantship, 1989-1991
- Presidential Scholar, Case Western Reserve University, 1975-1979
- National Merit Scholar, 1975-1979
Patents
- National Cancer Institute Invention Report "BRB ArrayTools - a desktop software package for the analysis of DNA microarray data" Inventors: R Simon, A Peng, L McShane, M Radmacher, R Taylor, and M Abramson. (2001)
- International Application No. PCT/US99/20942: New Invention: "Identification of Novel Viral Targets Containing Frameshifting Signals That Are Targets for Anti-viral Therapies" Inventors: JD Dinman, R Taylor, and SW Peltz. Filed: September 13, 1999. (1999)
Selected Publications
Taylor, R.C., Singhal, M., Daly, D.S., Domico, K., White, A.M., Auberry, D.L., Auberry, K.J., Hooker, B., Hurst, G., McDermott, J., McDonald, W.H., Pelletier, D., Schmoyer, D. and Cannon, W.R. (2007). "SEBINI-CABIN: an analysis pipeline for biological network inference, with a case study in protein-protein interaction network reconstruction." Proceedings of the Workshop on Machine Learning in Biomedicine and Bioinformatics of the Sixth International Conference on Machine Learning and Applications (ICMLA '07). December 13-15, 2007, Cincinnati, Ohio, 587-593.
Taylor, R.C., Shah, A., Treatman, C., Blevins, M. (2006). "SEBINI: Software Environment for BIological Network Inference." Bioinformatics 22(21):2706-2708.
Dinman, J.D., Richter, S., Plant, E., Taylor, R.C., Hammell, A.B., and TM Rana. (2002). "The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure." Proc. Nat. Acad. Sci. 99:5331-5336.
Edgerton, M.E., Taylor, R.C., Powell, J.I., Hunter, L., Simon, R., Liu, E.T. (2002). "A bioinformatics tool to select sequences for microarray studies of mouse models of oncogenesis." Bioinformatics 18:774-775.
Brazma, A., Hingamp, P., Quackenbush, J., Sherlock, G., Spellman, P., Stoeckert, C., Aach, J., Ansorge, W., Ball, C.A., Causton, H.C., Gaasterland, T., Glenisson, P., Holstege, F.C.P., Kim, I.F., Markowitz, V., Matese, J.C., Parkinson, H., Robinson, A., Sarkans, U., Schulze-Kremer, S., Stewart, J., Taylor, R.C., Vilo, J., Vingron, M. (2001). "Minimum information about a microarray experiment (MIAME) - toward standards for microarray data." Nature Genetics 29:365-371.
Hunter, L., Taylor, R.C., Leach, S.M., Simon, R. (2001). "GEST: A Gene Expression Search Tool Based on a Novel Bayesian Similarity Metric." Bioinformatics 17:115S-122S.