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Keqi Tang, Ph.D.

Expertise

Keqi Tang
Keqi Tang

Dr. Tang's research focuses on the development of advanced ion mobility spectrometry (IMS) instrumentation and methods for ultimate high throughput applications in system biology research. Current research projects include new technology development related to both conventional drift tube IMS and high field asymmetric waveform IMS (FAIMS) through extensive theoretical modeling and experimental evaluation. Other research efforts include mass spectrometry instrumentation with focus on the new ESI interface development and fundamentals of electrospray ionization.

Education

  • Ph.D., Mechanical Engineering, Yale University, 1994
  • M.S. & M.Ph., Mechanical Engineering, Yale University, 1992
  • M.S., Engineering Thermophysics, University of Science and Technology of China, 1987
  • B.S., Mathematical Mechanics, Tsinghua University, 1983

Honors and Awards

  • Federal Laboratory Consortium Award for Technology Transfer, 2004
  • Battelle key contributor award, 2004
  • Battelle key contributor award, 2003

Professional Affiliations

  • American Society for Mass Spectrometry

Selected Publications

K. Tang, F. Li, A. A. Shvartsburg, E. F. Strittmatter, R. D. Smith. 2005. "Two-Dimensional Gas-Phase Separations Coupled to Mass Spectrometry for Analyses of Complex Mixtures." Anal. Chem., 77, 6381-6388.

K. Tang, A. A. Shvartsburg, H. Lee, D. C. Prior, M. A. Buschbach, F. Li, A. Tolmachev, G. A. Anderson and R. D. Smith, 2005 "High-Sensitivity Ion Mobility Spectrometry/Mass Spectrometry Using Electrodynamic Ion Funnel Interfaces." Anal. Chem., 77, 3330-3339.

A. A. Shvartsburg, K. Tang and R. D. Smith. 2004. "Understanding and designing the FAIMS separations in gas mixtures." Anal. Chem., 76, 7366-7374.

R. D. Smith, Y. Shen and K. Tang. 2004. "Ultra-sensitive and quantitative analyses from combined separations-mass spectrometry for the characterization of proteomes." Acc. Chem. Res., 37, 269-278.

E. F. Strittmatter, P. L. Ferguson, K. Tang, and R. D. Smith. 2003. "Proteome Analyses Using Accurate Mass and Elution Time Peptide Tags with Capillary LC Time-of-Flight Mass Spectrometry." J. Am. Soc. Mass Spectrom., 14, 980-991.

Contact Information

Systems Biology at PNNL

Research & Capabilities

Resources