Heidi J. Sofia, Ph.D.
Expertise

Heidi Sofia
Primary interests are using sophisticated bioinformatics tools for discovery research in biology and in developing problem solving environments using visual and computational approaches.
Education
- Ph.D., Biochemistry, University of Wisconsin, 1993
- M.P.H., Public Health/Biochemical Toxicology, University of California, 1986
- B.A., Biochemistry, University of California, 1984
Honors and Awards
- National Merit Scholarship (Undergraduate)
- WARF Fellowship (Graduate)
- National Science Foundation Fellowship (Graduate)
Professional Affiliations
- American Association for the Advancement of Science
Selected Publications
Korner H, HJ Sofia, and WG Zumft. 2003. "Phylogeny of the bacterial superfamily of Crp-Fnr transcription regulators: exploiting the metabolic spectrum by controlling alternative gene programs." FEMS Microbiology Reviews 27(5):559-592.
Kajkowski EM, CF Lo, X Ning, S Walker, HJ Sofia, W Wang, W Edris, P Chandra, E Wagner, S Vile, K Ryan, B McHendry-Rinde, SC Smith, A Wood, KJ Rhodes, JD Kennedy, J Bard, JS Jacobsen, and BA Ozenberger. 2001. "Beta-amyloid peptide-induced apoptosis regulated by a novel protein containing a G protein activation module." J. Biol. Chem. 276(22):18748-18756.
Sofia HJ, G Chen, BG Hetzler, JF Reyes-Spindola, and NE Miller. 2001. "Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: Discovery and functional characterization using new analysis and information visualization methods." Nucleic Acids Research 29(5):1097-1106.
Saffer JD, CL Albright, AJ Calapristi, G Chen, VL Crow, SD Decker, KM Groch, SL Havre, JM Malard, TJ Martin, NE Miller, PJ Monroen, LT Nowell, DA Payne, JF Reyes Spindola, RE Scarberry, HJ Sofia, LC Stillwell, GS Thomas, SJ Thurston, LK Williams, and SJ Zabriskie. 2001. "Visualization and Integrated Data Mining of Disparate Information." Chemical Data Analysis in the Large: The Challenge of the Automation Age, Proceedings of the Beilstein-Institut International Workshop, May 22-26, 2000, Bozen, Italy , ed. MG Hicks. Beilstein-Institut, Frankfurt am Main, Germany.
Burland V, Y Shao, NT Perna, G Plunkett, HJ Sofia, and FR Blattner. 1998. "The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7." Nucleic Acids Research 26(18):4196-204.
