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Liang Shi, Ph.D.


Liang Shi
Liang Shi

Dr. Shi's current research areas include: (1) the electron transport network of Shewanella oneidensis MR-1 and (2) Salmonella-macrophage interaction by systems biology approach. Dr. Shi is the author and co-author over 45 peer-reviewed publications.


  • Ph.D., Biomedical Science, Wright State University, 1996
  • M.S., Biological Sciences, Wright State University, 1992
  • M.S., Plant Pathology, Huazhong Agricultural University, 1985
  • B.S., Plant Protection, Huazhong Agricultural University, 1982

Professional Affiliations

  • American Society for Microbiology
  • American Society for Biochemistry and Molecular Biology
  • Served as a reviewer for the Journal of Bacteriology, Molecular Microbiology, Journal Biotechnology, Microbiology, FEMS Microbiology Letter, ISME J, RNA, Extremophiles, International Journal of Environmental Analytical Chemistry and Soil & Sediment Contamination: an International Journal

Selected Publications

Wang Z, C Liu, X Wang, MJ Marshall, JM Zachara, KM Rosso, M Dupuis, JK Fredrickson, S Heald, and L Shi. 2008. "Reduction kinetics of Fe(III) complexes by outer membrane cytochromes MtrC and OmcA of Shewanella oneidensis MR-1." Applied and Environmental Microbiology. 74: 6746-6755.

Shi L, S Deng, MJ Marshall, Z Wang, DW Kennedy, AC Dohnalkova, HM Mottaz, EA Hill, YA Gorby, AS Beliaev, DJ Richardson, JM Zachara, and JK Fredrickson. 2008. "Direct involvement of type II secretion system in extracellular translocation of Shewanella oneidensis outer membrane cytochromes MtrC and OmcA." Journal of Bacteriology 190: 5512-5516.

Shi L, TC Squier, JM Zachara and JK Fredrickson. 2007. "Respiration of metal (hydr)oxides by Shewanella and Geobacter: A key role for multiheme c-type cytochromes." Molecular Microbiology 65: 12-20.

Shi L, JN Adkins, JR Coleman, A Dohnalkova, AA Schepmoes, HM Mottaz, AD Norbeck, SO Purvine, HS Smallwood, J Forbes, P Gros, S Uzzau, KD Rodland, F Heffron, RD Smith, and TC Squier. 2006. "Proteomic analysis of Salmonella enterica serovar Typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar Typhimurium inside macrophages." Journal of Biological Chemistry. 281:29131-29140.

Contact Information

Systems Biology at PNNL

Research & Capabilities