Haluk Resat, Ph.D.
Expertise
Haluk Resat
Dr. Resat has an interdisciplinary background integrating engineering with physical sciences and biology. His current research interests include biological network construction and verification, kinetic simulations of biological systems, control analysis, investigation of regulatory interactions in biological networks, analysis of experimental data to derive quantitative properties from measurements, experimental design and the use of a systems approach to biological sciences, and development of multiscale methods to study biological processes.
Education
- Postdoc, University of California at San Diego, 1994-96
- Postdoc, Mount Sinai School of Medicine, New York, 1992-94
- Ph.D., Physics, State University of New York at Stony Brook, 1992
- B.S., Electrical Engineering, Bosphorus University, Istanbul, Turkey, 1986
- B.S., Physics, Bosphorus University, Istanbul, Turkey, 1986
Honors and Awards
- Recipient of the 1998 Promising Young Scientist Award, National Scientific and Technological Research Institute of Turkey, (TUBITAK, equivalent of NSF in Turkey).
- Recipient of Fellowship for the Advancement of Science, National Scientific and Technological Research Institute of Turkey (1978-86).
Professional Affiliations
- Membership: Biophysical Society, International Society for Computational Biology, Society for Industrial and Applied Mathematics, American Society of Cell Biology, International Receptor Tyrosine Kinase Consortium (founding member).
- Reviewer for: Bioinformatics; Biophysical Journal; BMC Bioinformatics; BMC Genomics; BMC Systems Biology; Bulletin for Mathematical Biology; European Journal of Biochemistry; FEBS Journal; FEBS Letters; In Silico Biology; Journal of American Chemical Society; Journal of Cellular Physiology; Journal of Chemical Physics; Journal of Chemical Theory and Computation; Journal of Computational Chemistry; Journal of Computer-Aided Molecular Design; Journal of Physical Chemistry; Molecular BioSystems;Molecular Medicine; Molecular Systems Biology; Nature Structural Biology; Pacific Symposium on Biocomputing; Physical Review E; Physical Review Letters; PLoS ONE; Protein Science; Theoretical Biology and Medical Modeling.
- Scientific reviewer for: DOE-SBIR/STTR program; NSF Career Awards; NSF-RUI Research at Undergraduate Institutions Program; NSF University-Industry Fellowship Program; Petroleum Research Fund/American Chemical Society; Cell Systems Initiative, University of Washington; Department of Pharmacology, University of California-San Diego; PNNL Data Intensive Computing Initiative; PNNL Environmental Biomarkers Initiative; PNNL Biomolecular Systems Initiative.
- Review Panelist for NIH and NSF.
Selected Publications
"Quantifying the effects of EGFR-HER2 co-expression on HER activation and trafficking," Harish Shankaran, Yi Zhang, Lee Opresko, and Haluk Resat, Biochemical and Biophysical Research Communications 371, 220-224 (2008).
"Cell surface receptors for signal transduction and ligand transport: A design principles study," Harish Shankaran, Haluk Resat, and H. Steven Wiley, PLoS Computational Biology, 3 (6) e101 doi:10.1371/journal.pcbi.0030101 (2007).
"Modeling the effects of HER/ErbBs 1-3 coexpression on receptor dimerization and biological response," Harish Shankaran, H. Steven Wiley, and Haluk Resat, Biophysical J. 90, 3993-4009 (2006).
"A domain based approach to predict protein-protein interactions," Mudita Singhal and Haluk Resat, BMC Bioinformatics 8, 199 (2007).
"Combining microarray and genomic data to predict DNA binding motifs," Linyong Mao, R. Chris Mackenzie, Jung H. Roh, Jesus M. Eraso, Samuel Kaplan, and Haluk Resat, Microbiology 151, 3197-3213 (2005). Highlighted in the Nature Reviews Microbiology as the selected Bioinformatics paper (Nov. 2005).