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William F. Morgan, Ph.D., D.Sc.

Expertise

William Morgan
William F. Morgan

Dr. William F. Morgan is the Director of Radiation Biology and Biophysics in the Biological Sciences Division at the Pacific Northwest National Laboratory (PNNL) in Richland, WA. Dr. Morgan joined the staff at PNNL in August 2008 to lead the systems radiation biology initiative. His research has focused on the long-term effects of exposure to low doses of ionizing radiation, specifically the molecular, biochemical, cytogenetic, cellular and tissue responses to low doses of radiation and how these might translate into potential cancer risks.

Education

  • D.Sc. University of Canterbury, Christchurch, New Zealand. 2003
  • Ph.D. University of Canterbury, Christchurch, New Zealand. 1980
  • M.Sc. (with distinction). University of Canterbury, Christchurch, New Zealand. 1977.
  • B.Sc. University of Canterbury, Christchurch, New Zealand. 1975.

Honors and Awards

  • NCI Scientific Review Group Subcommittee C, 1998 – 2003; Chairman 2001-2003
  • Member U.S. Department of Energy's Scientific Review Group for the Russian health Studies Program, 2005-2008
  • National Academy of Sciences Board on Radiation Effects Research 1998 - 2004
  • National Council on Radiation Protection and Measurements (NCRP) 2002 –2014
  • Vice President of Program Area Committee (PAC) 1 that oversees work on basic criteria, epidemiology, radiobiology and risk, 2008 - present
  • International Council on Radiation Protection (ICRP) 2005 - 2010
  • European Community's Non-Targeted Effects of Ionizing Radiation (NOTE) Consortium; Chairman of External Advisory Board 2006 - 2011
  • United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) Consultant 2003 - present
  • Executive Editor: Mutagenesis: 1994 – 2000
  • Editorial Board: Radiation Research; 1994 – 1998
    • Environmental and Molecular Mutagenesis; 1989 - present
    • Mutation Research: 1990 - present

Selected Publications

Morales, M., Liu, Y., Laiakis, E.C., Morgan, W.F., Nimer, S.D., and Petrini, J.H.J. (2008). "DNA damage signaling in hematopoietic cells: A role for Mre11 complex repair of topoisomerase lesions." Cancer Res., 68, 2186-2193 .

Huang, L., Nickoloff, J.A., Kim, P.M. and Morgan, W.F. (2007). "Targeted and non-targeted effects of low-dose ionizing radiation on delayed genomic instability in human cells." Cancer Res. 67, 1099-1104.

Durant, S.T., Paffett, K.S., Shrivastav, M., Timmins, G.S., Morgan, W.F. and Nickoloff, J.A. (2006). "UV radiation induces delayed hyperrecombination associated with hypermutation in human cells." Mol. Cell Biol. 26, 6047-6055.

Kim, G.J., Fiskum, G. and Morgan, W.F. (2006). "A role for mitochondrial dysfunction in perpetuating radiation induced genomic instability." Cancer Res. 66, 10377-10383.

Snyder, A.R. and Morgan, W.F. (2005). "Lack of consensus gene expression changes associated with radiation-induced chromosomal instability." DNA Repair 4, 958-970.

Contact Information

Systems Biology at PNNL

Research & Capabilities

Resources